Alternative Names: Throat lesion biopsy; Biopsy - mouth or throat; Mouth lesion biopsy

How the test is performed:

A pain-killer or numbing agent is usually used on the area. For large sores or sores of the throat, a general anesthetic that puts the patient to sleep may be needed. The entire lesion, or a small portion of larger lesions, is removed and sent to the laboratory to check for problems. If there is a growth in the mouth or throat, the biopsy may be the first part of tumor removal.

How to prepare for the test:

If a simple pain-killer or numbing agent is to be used, there is no special preparation. If the test is part of a tumor removal or if general anesthetic is to be used, you may be told not to eat for 6 - 8 hours before the test.

How the test will feel:

There may feelings of pressure or tugging during removal of the tissue. If there is bleeding, cautery (sealing of blood vessels with electric current or laser) may be needed. After the numbness wears off, the area may be sore for a few days.

Why the test is performed:

This test is done to find the cause of a sore (lesion) in the throat.

Normal Values:

This test is only performed when there is an abnormal lesion (abnormal tissue area).

What abnormal results mean:

• Histoplasmosis
• Fungal infections (such as candida)
• Viral infections (such as Herpes simplex)
• Cancer of the oropharynx (such as squamous cell carcinoma)
• Precancerous lesion (leukoplakia)

Oral lichen planus is another condition under which the test may be performed.

What the risks are:

• Infection of the site
• Bleeding from the site

Special considerations:

Avoid hot or spicy food after the biopsy.